UNOOSA Director, Ms. Simonetta Di Pippo, leads the Office's strategies, policies and activities, ensuring that they are implemented in accordance with the mandates of the General Assembly, the Committee on the Peaceful Uses of Outer Space (COPUOS), and the established policies of the United Nations. She supervises the United Nations Programme on Space Applications and UN-SPIDER.

Ms. Di Pippo advises the Secretary-General of the United Nations and Director-General of UNOV and provides expertise on matters relating to the peaceful uses of outer space, and the use of space science and technology for sustainable development and disaster risk reduction. Ms. Di Pippo also discharges the Secretary-General's obligations under international space law, including overseeing the United Nations Register of Objects Launched into Outer Space. She serves as Secretary of COPUOS and manages the arrangements and coordination of UN-Space.

Alongside her team in the Office of the Director, Ms. Di Pippo co-ordinates and oversees reports on budgetary and programme performance matters as well as public information and outreach activities to promote the benefits of outer space for humanity.